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Dextroamphetamine ER (Dexedrine Spansule) is an expensive drug used to treat attention-deficit hyperactivity disorder (ADHD). This drug is less popular than comparable drugs. It is available in brand and generic versions. Generic dextroamphetamine ER is covered by most Medicare and insurance plans, but some pharmacy coupons or cash prices may be lower. The lowest GoodRx price for the most common version of dextroamphetamine ER is around $104.48, 69% off the average retail price of $343.11. Compare central nervous system stimulants.